Dr. Brem's
Patents and
Patent Applications
Following our model of patient-driven translational research, Dr. Harold Brem and his professional colleagues have been involved in the development of a number of new drug therapies and treatment methods for chronic wounds.
At present, the center has been granted a patent or has a pending patent application related to the following discoveries. For a full description of each, click on the title of the individual patent or patent application:
Patents Granted
United States Patent 7,919,478
Inventor: Harold Brem
April 5, 2011
Title: Method for treating diabetic ulcers with vectors encoding VEGF
Pending Patent Applications
U.S. Patent Application No. 20080274079
Inventor: Marjana Tomic-Canic and Harold Brem
November 6, 2008
Title: De novo synthesis of glucocorticoids in the epidermis and its uses and applications
U.S. Patent Application No. 20090191156
Inventor: Harold Brem and Marjana Tomic-Canic
July 30, 2009
Title: GM-CSF cosmeceutical compositions and methods of use thereof
U.S. Patent Application No. 20090203006
Inventor: Harold Brem and Marjana Tomic-Canic
August 13, 2009
Title: Biological markers of chronic wound tissue and methods of using for criteria in surgical debridement
U.S. Patent Application 20100310517
Inventor: Harold Brem and Marjana Tomic-Canic
December 9, 2010
Title: Growth factor mediated cosmeceuticals and use thereof to enhance skin quality
U.S. Patent Application 20110190372
Inventor: Harold Brem, and Marjana Tomic-Canic
August 4, 2011
Title: Compositions and methods for treating inflammatory disorders