How is Human Skin Equivalent (HSE) used to heal diabetic ulcers?
Healing of a diabetic toe ulcer.
Figure A: Diabetic patient with toe ulcers before treatment with bilayered living human skin equivalent (HSE).
Figure B: HSE, as it arrives in transwell, immediately before application.
Figure C: Same toe ulcers, immediately following application of HSE.
Figure D: Toe ulcers healed in 35 days.
Clinical Efficacy and Mechanism of Bilayered Living Human Skin Equivalent (HSE) in Treatment of Diabetic Foot Ulcers
Harold Brem, M.D., Jan Young, Ph.D., Cary Isaacs, M.S.,Marjana Tomic-Canic, Ph.D.
H. Paul Ehrlich, Ph.D.